[Primary cutaneous leiomyosarcoma: 32 cases].

摘要: Background Superficial leiomyosarcomas are rare tumors, which may be confined to the dermis or extend subcutaneous tissues. Patients and methods We report results of a retrospective study 32 patients treated for through twenty-two year period (from 1975 1997). Results Mean age was 45 years, with 50 p. 100 less than 35 years age. Forty seven percent tumors were located on lower limbs mean diameter 2.8 cm. Three clinical types have been isolated: nodule beneath normal epidermis (50 100), purple ulcerated not (28 swelling tumor (22 100). Sixteen intradermal, whereas sixty nine involved With regard grade, 37 grade I, 44 II, 19 III. Immunohistochemical staining showed positive reactions all anti-vimentin anti-alpha smooth muscle actin. Main treatment complete surgical excision. Follow-up informations available 75 them had follow up longer year. Five involving subcutis developed local recurrences, two died disease. Discussion Leiomyosarcomas can occur at any without predominant sex-ratio. prognostic factors size, distal location, depth invasion pathological grade. Immunohistological actin is more sensitive specific anti-desmin anti-HHF 35. excision wide margins.