作者: Daniela Massi , Alessandro Franchi , Llucia Alos , Martin Cook , Silvana Di Palma
DOI: 10.1111/J.1365-2559.2009.03471.X
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摘要: Massi D, Franchi A, Alos L, Cook M, Di Palma S, Enguita A B, Ferrara G, Kazakov D V, Mentzel T, Michal Panelos J, Rodriguez-Peralto J Santucci Tragni Zioga & Tos P D (2010) Histopathology56, 251–262 Primary cutaneous leiomyosarcoma: clinicopathological analysis of 36 cases Aims: Cutaneous leiomyosarcomas (LMS) are rare in comparison with their deep-seated soft tissue and uterine counterparts, have been poorly characterized. The aim was to verify whether the clinical behaviour purely dermal LMS is different from that minimal subcutis invasion. Methods results: Twenty-one 15 extension were analysed. Tumours developed 27 men nine women (age range 29–91 years); most tumours showed a fasciculated (n = 23), pilar-type (n = 12) pleomorphic (n = 1) pattern. During follow-up period (range 2–192, mean 41 months) recurrences occurred 1/16 (6.2%) confined dermis 2/11 (18.1%) extension. three recurrent high-grade LMS, two which exhibited myxoid areas. One patient into fat distant metastases 15 years after diagnosis. Conclusions: For involving skin, it advisable recognize indicate histopathology report depth and/or subcutaneous extension, since even involvement may be associated late local metastases, therefore appropriate long-term needed.