Neurotoxic effects of endocrine disruptors

作者: Susan A. Laessig , Margaret M. McCarthy , Ellen K. Silbergeld

DOI: 10.1097/00019052-199912000-00015

关键词:

摘要: Endocrine disrupting chemicals are a newly defined category of environmental contaminants that may affect animal and human populations by interfering with normal hormone action. There is substantial concern these agents could have range subtle long-lasting effects. Because the sensitivity developing central nervous system to low levels endogenous gonadal hormones during development, be target for action endocrine chemicals.

参考文章(66)
Eriksson P, Developmental neurotoxicity of environmental agents in the neonate. Neurotoxicology. ,vol. 18, pp. 719- 726 ,(1997)
Catherine S. Woolley, Nancy G. Weiland, Bruce S. McEwen, Philip A. Schwartzkroin, Estradiol Increases the Sensitivity of Hippocampal CA1 Pyramidal Cells to NMDA Receptor-Mediated Synaptic Input: Correlation with Dendritic Spine Density The Journal of Neuroscience. ,vol. 17, pp. 1848- 1859 ,(1997) , 10.1523/JNEUROSCI.17-05-01848.1997
Jessica A. Mong, Edmund Glaser, Margaret M. McCarthy, Gonadal Steroids Promote Glial Differentiation and Alter Neuronal Morphology in the Developing Hypothalamus in a Regionally Specific Manner The Journal of Neuroscience. ,vol. 19, pp. 1464- 1472 ,(1999) , 10.1523/JNEUROSCI.19-04-01464.1999
Frederick S vom Saal, Barry G Timms, Monica M Montano, Paola Palanza, Kristina A Thayer, Susan C Nagel, Minati D Dhar, VK Ganjam, Stefano Parmigiani, Wade V Welshons, Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses Proceedings of the National Academy of Sciences of the United States of America. ,vol. 94, pp. 2056- 2061 ,(1997) , 10.1073/PNAS.94.5.2056
Prasada Rao S. Kodavanti, Thomas R. Ward, Ethel C. Derr-Yellin, William R. Mundy, Ann C. Casey, Brian Bush, Hugh A. Tilson, Congener-Specific Distribution of Polychlorinated Biphenyls in Brain Regions, Blood, Liver, and Fat of Adult Rats Following Repeated Exposure to Aroclor 1254☆☆☆★ Toxicology and Applied Pharmacology. ,vol. 153, pp. 199- 210 ,(1998) , 10.1006/TAAP.1998.8534
A. S. Faqi, I. Chahoud, Antiestrogenic Effects of Low Doses of 2,3,7,8-TCDD in Offspring of Female Rats Exposed Throughout Pregnancy and Lactation Bulletin of Environmental Contamination and Toxicology. ,vol. 61, pp. 462- 469 ,(1998) , 10.1007/S001289900785
M.M. McCarthy, H.R. Besmer, S.C. Jacobs, G.M.O. Keidan, R.B. Gibbs, Influence of maternal grooming, sex and age on Fos immunoreactivity in the preoptic area of neonatal rats: implications for sexual differentiation. Developmental Neuroscience. ,vol. 19, pp. 488- 496 ,(1997) , 10.1159/000111246
R J Kavlock, G P Daston, C DeRosa, P Fenner-Crisp, L E Gray, S Kaattari, G Lucier, M Luster, M J Mac, C Maczka, R Miller, J Moore, R Rolland, G Scott, D M Sheehan, T Sinks, H A Tilson, Research needs for the risk assessment of health and environmental effects of endocrine disruptors: a report of the U.S. EPA-sponsored workshop. Environmental Health Perspectives. ,vol. 104, pp. 715- 740 ,(1996) , 10.1289/EHP.96104S4715