Pathology of Chromosome Abnormalities in First Trimester Embryos

摘要: Prenatal diagnosis following early amniocentesis and ultrasonography has encouraged systematic fetopathological investigations of developmental disorders during the second trimester pregnancy. It been shown that characteristic features known chromosomal syndromes can be easily recognized in fetus 16th–24th week gestation, which may help to identify syndromal diseases spontaneous abortions a prenatal was lacking. Furthermore, it become evident chromosomally abnormal fetuses present with patterns malformations are at once more severe specific than those affected newborns, indicating high abortion rate for even late pregnancy (Rehder 1979,1982).