Criteria for essential fatty acid deficiency in plasma as assessed by capillary column gas-liquid chromatography.
作者： E N Siguel , K M Chee , J X Gong , E J Schaefer
DOI: 10.1093/CLINCHEM/33.10.1869
关键词:
摘要: To develop criteria for deficiency of essential fatty acids (EFA), we used capillary-column gas-liquid chromatography to determine (percentage total acids) in plasma obtained the fasting state from 56 reference subjects and 10 patients with intestinal fat malabsorption suspected EFA deficiency. Fatty acid evaluations that allowed a clear distinction (P less than 0.01) between patients, based on values two standard deviations below or above mean, included linoleic (18:2w6) 27%, palmitic (16:0), palmitoleic (16:1w7), oleic (18:1w9), vaccenic (18:1w7), Mead (20:3w9) exceeding 21%, 2.6%, 23.3%, 2.1%, 0.21%, respectively. Ratios non-EFA 0.60 arachidonic greater 0.025 also served identify were not found subjects. Significant inverse correlations percentages mono-unsaturated noted. Our reference-interval data can be assess normality status.
oup.com
aaccjnls.org参考文章(4)
Ralph T. Holman, Essential fatty acid deficiency Progress in The Chemistry of Fats and Other Lipids. ,vol. 9, pp. 275- 348 ,(1971) , 10.1016/0079-6832(71)90030-9
Keith L. Black, Brenda Culp, Diane Madison, Otelio S. Randall, William E.M. Lands, The protective effects of dietary fish oil on focal cerebral infarction Prostaglandins and Medicine. ,vol. 3, pp. 257- 268 ,(1979) , 10.1016/0161-4630(79)90067-3
T A Miettinen, V Naukkarinen, J K Huttunen, S Mattila, T Kumlin, Fatty-acid composition of serum lipids predicts myocardial infarction. BMJ. ,vol. 285, pp. 993- 996 ,(1982) , 10.1136/BMJ.285.6347.993
S H Goodnight, W S Harris, W E Connor, D R Illingworth, Polyunsaturated fatty acids, hyperlipidemia, and thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 2, pp. 87- 113 ,(1982) , 10.1161/01.ATV.2.2.87