Differential ANG II generation in plasma and tissue of mice with decreased expression of the ACE gene.
作者： Chih-Chang Wei , Baohong Tian , Gilbert Perry , Qing Cheng Meng , Yiu-Fai Chen
DOI: 10.1152/AJPHEART.00191.2001
关键词:
摘要: We utilized mice with homozygous disruption of angiotensin-converting enzyme (ACE) (−/−), heterozygous deletion ACE (+/−), and wild-type (+/+) to test the hypothesis that genetic ...
sci-hub.se 参考文章(23)
Naotaka SHIOTA, Akiyoshi FUKAMIZU, Hideki OKUNISHI, Shinji TAKAI, Kazuo MURAKAMI, Mizuo MIYAZAKI, Cloning of the gene and cDNA for hamster chymase 2, and expression of chymase 1, chymase 2 and angiotensin-converting enzyme in the terminal stage of cardiomyopathic hearts. Biochemical Journal. ,vol. 333, pp. 417- 424 ,(1998) , 10.1042/BJ3330417
H Urata, A Kinoshita, K S Misono, F M Bumpus, A Husain, Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart. Journal of Biological Chemistry. ,vol. 265, pp. 22348- 22357 ,(1990) , 10.1016/S0021-9258(18)45712-2
C F Reilly, D A Tewksbury, N M Schechter, J Travis, Rapid conversion of angiotensin I to angiotensin II by neutrophil and mast cell proteinases. Journal of Biological Chemistry. ,vol. 257, pp. 8619- 8622 ,(1982) , 10.1016/S0021-9258(18)34171-1
U. M. Chandrasekharan, S. Sanker, M. J. Glynias, S. S. Karnik, A. Husain, Angiotensin II-Forming Activity in a Reconstructed Ancestral Chymase Science. ,vol. 271, pp. 502- 505 ,(1996) , 10.1126/SCIENCE.271.5248.502
Naotaka Shiota, Akiyoshi Fukamizu, Shinji Takai, Hideki Okunishi, Kazuo Murakami, Mizuo Miyazaki, Activation of angiotensin II-forming chymase in the cardiomyopathic hamster heart. Journal of Hypertension. ,vol. 15, pp. 431- 440 ,(1997) , 10.1097/00004872-199715040-00014
Arlene Wolny, Jean-Paul Clozel, Josiane Rein, Paul Mory, Paul Vogt, Marko Turino, Wolfgang Kiowski, Walter Fischli, Functional and Biochemical Analysis of Angiotensin II–Forming Pathways in the Human Heart Circulation Research. ,vol. 80, pp. 219- 227 ,(1997) , 10.1161/01.RES.80.2.219
Gilbert J. Perry, Tatsuhiko Mori, Chih-Chang Wei, Xiao Yan Xu, Yiu-Fai Chen, Suzanne Oparil, Pamela Lucchesi, Louis J. Dell’Italia, Genetic Variation in Angiotensin-Converting Enzyme Does Not Prevent Development of Cardiac Hypertrophy or Upregulation of Angiotensin II in Response to Aortocaval Fistula Circulation. ,vol. 103, pp. 1012- 1016 ,(2001) , 10.1161/01.CIR.103.7.1012
Naotaka Shiota, Denan Jin, Shinji Takai, Toru Kawamura, Mamoru Koyama, Norifumi Nakamura, Mizuo Miyazaki, Chymase is activated in the hamster heart following ventricular fibrosis during the chronic stage of hypertension FEBS Letters. ,vol. 406, pp. 301- 304 ,(1997) , 10.1016/S0014-5793(97)00295-0
John H. Krege, Simon W. M. John, Laura L. Langenbach, Jeffrey B. Hodgin, John R. Hagaman, Eric S. Bachman, J. Charles Jennette, Deborah A. O'Brien, Oliver Smithies, Male–female differences in fertility and blood pressure in ACE-deficient mice Nature. ,vol. 375, pp. 146- 148 ,(1995) , 10.1038/375146A0
P Gohlke, P Bünning, T Unger, Distribution and metabolism of angiotensin I and II in the blood vessel wall. Hypertension. ,vol. 20, pp. 151- 157 ,(1992) , 10.1161/01.HYP.20.2.151