Convergence on interneurones in the reciprocal Ia inhibitory pathway to motoneurones.

摘要: Summary 1. The present studies have aimed at analyzing the excitatory and inhibitory convergence from various neuronal systems onto inter-neurones mediating reciprocal inhibition of motoneurones large muscle spindle (Ia) afferents. conclusions regarding on Ia interneurones rest how transmission in pathway is influenced other systems; an being indicated by facilitation depression IPSPs. IPSPs volleys motor axon collaterals has also been important tool analysis. 2. It known that afferents several muscles often can evoke a given species motoneurones. now demonstrated this convergence, least partly, takes place already interneuronal level. 3. In spinal cats under chloralose anesthesia flexor as well extensor were regularly facilitated cutaneous high threshold joint decerebrate with low pontine lesion (in which these both motoneurones) was not but depressed Volleys afferents, hand, preparation. postulated receive actions ipsi-lateral reflex (transmission state) through separate afferents. 4. A bulk evidence gathered demonstrating segmental descending pathways, control transmission, fact do converge same interneurones. Thus pool to nucleus so far be regarded functionally homogeneous. 5. Whenever conditioning ventral root or pathways found facilitate transmission. recurrent indicaces extent are mediated interneurones. 6. investigation relative contribution different efferent nerves revealed strongest always evoked fibres whose produce For example, IPSP knee recorded most effectively antidromic stimulation extensor. prevailing pattern effects indicates activity one will cause aL- γ-moto-neurones within nuclei innervating synergists impinging antagonists. 7. discussed light recently introduced concept “α-γ-linkage inhibition”.