Comparison of medical abortion with surgical vacuum aspiration: women's preferences and acceptability of treatment.

作者: R C Henshaw , S A Naji , I T Russell , A A Templeton

DOI: 10.1136/BMJ.307.6906.714

关键词:

摘要: OBJECTIVES--To assess women's preferences for, and the acceptability of, medical abortion vacuum aspiration in early first trimester. DESIGN--Patient centred, partially randomised trial. Medical was performed with mifepristone 600 mg followed 48 hours later by gemeprost 1 vaginal pessary. Vacuum under general anaesthesia. SETTING--Teaching hospital Scotland. PATIENTS--363 women undergoing legal induced at less than nine weeks' gestation. MAIN OUTCOME MEASURES--Women's for method of before abortion; judged two weeks after recording would opt to undergo future semantic differential rating technique. RESULTS--73 (20%) preferred abortion, 95 (26%) aspiration; 195 (54%) were willing either method, allocated random. Both procedures highly acceptable preferences. Gestation had a definite effect on women; 50 days there no differences, but between 63 significantly more acceptable. CONCLUSIONS--Women who wish use particular should be allowed their choice, regardless Women 50-63 days' gestation without are likely find A patient trial design may useful tool pragmatic research.

参考文章(20)
Edward E. Wallach, Robert G. Castadot, Pregnancy termination: techniques, risks, and complications and their management. Fertility and Sterility. ,vol. 45, pp. 5- 17 ,(1986) , 10.1016/S0015-0282(16)49089-8
Daniel Schwartz, Joseph Lellouch, Explanatory and Pragmatic Attitudes in Therapeutical Trials Journal of Clinical Epidemiology. ,vol. 62, pp. 499- 505 ,(2009) , 10.1016/J.JCLINEPI.2009.01.012
Andre Ulmann, Louise Silvestre, Laurence Chemama, Yvonne Rezvani, Marguerite Renault, Claude J. Aguillaume, Etienne-Emile Baulieu, Medical termination of early pregnancy with mifepristone (RU 486) followed by a prostaglandin analogue: Study in 16, 369 women Acta Obstetricia et Gynecologica Scandinavica. ,vol. 71, pp. 278- 283 ,(1992) , 10.3109/00016349209021052
C. R. Brewin, C. Bradley, Patient preferences and randomised clinical trials. BMJ. ,vol. 299, pp. 313- 315 ,(1989) , 10.1136/BMJ.299.6694.313
A-S Rosén, K von Knorring, M Bygdeman, N.J. Christensen, Randomized comparison of prostaglandin treatment in hospital or at home with vacuum aspiration for termination of early pregnancy. Contraception. ,vol. 29, pp. 423- 435 ,(1984) , 10.1016/0010-7824(84)90016-7
Anne-Sofie Rosén, Lars Nystedt, Marc Bygdeman, Viveca Lundström, Acceptability of a nonsurgical method to terminate very early pregnancy in comparison to vacuum aspiration Contraception. ,vol. 19, pp. 107- 117 ,(1979) , 10.1016/S0010-7824(79)80023-2