作者: Oscar D. Bruno , Leonardo F. L. Rizzo
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摘要: Amiodarone and thyroid dysfunction. is a structural analogue of hormone, some its anti-arrhythmic actions toxicity are attributable to interaction with nuclear recep- tors hormones. Being highly lipophilic, amiodarone concentrated in many tissues eliminated, consequently, very slowly. It preferably employed manage life-threatening arrhythmias, including ventricular fibrillation unstable tachycardia. Other indications include atrial flutter, severe congestive heart failure, prevention recurrence, even emergency medical situations prevent sudden cardiac death. The aim this review provide an updated approach on influence physiology discuss analyze depth potential not infrequent thyroidal adverse effects such as hypothyroidism thyrotoxicosis.