Analysis of Mitochondrial Genome Alterations in Cancer

作者: Gabriel D. Dakubo

DOI: 10.1007/978-3-642-11416-8_13

关键词:

摘要: Clinical measurements of mitochondrial genome changes in cancer is as important assessing this cytopathies. Polymorphisms, somatic point mutations, well large-scale deletions and content are all applicable management. Proper sample preparation attention to technical details issues assaying authentic clinical specimens. This chapter examines several available methods measuring mtDNA mutations quantitative deletions. Important precautions needed for good assay performance provided well.

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