The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

作者: Angela M. Krebs , Julia Mitschke , María Lasierra Losada , Otto Schmalhofer , Melanie Boerries

DOI: 10.1038/NCB3513

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摘要: … Here, we describe a key role for the EMT-TF Zeb1 in the in vivo progression of pancreatic cancer from early precursor lesions towards metastasis. Genetic depletion of Zeb1 in the …

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