Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one.
作者： Claudiu T. Supuran , Vincenzo Alterio , Anna Di Fiore , Katia D’ Ambrosio , Fabrizio Carta
DOI: 10.1002/MED.21497
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摘要: … , HIF-1α accumulates in the cell, translocates to the nucleus, and dimerizes with HIF-1β forming an active HIF-1, which interacts with transcriptional co-activators p300/CBP and binds to …
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