4D cardiovascular magnetic resonance velocity mapping of alterations of right heart flow patterns and main pulmonary artery hemodynamics in tetralogy of Fallot

作者: Christopher J François , Shardha Srinivasan , Mark L Schiebler , Scott B Reeder , Eric Niespodzany

DOI: 10.1186/1532-429X-14-16

关键词:

摘要: To assess changes in right heart flow and pulmonary artery hemodynamics patients with repaired Tetralogy of Fallot (rTOF) we used whole heart, four dimensional (4D) velocity mapping (VM) cardiovascular magnetic resonance (CMR). CMR studies were performed 11 subjects rTOF (5M/6F; 20.1 ± 12.4 years) 10 normal volunteers (6M/4F; 34.2 13.4 on clinical 1.5T 3.0T MR scanners. 4D VM-CMR was using PC VIPR (Phase Contrast Vastly undersampled Isotropic Projection Reconstruction). Interactive streamline particle trace visualizations the superior inferior vena cava (IVC SVC, respectively), atrium (RA), ventricle (RV), (PA) generated reviewed by three experienced readers. Main PA net flow, retrograde peak time-to-peak acceleration, resistance index mean wall shear stress quantified. Differences patterns between two groups tested Fisher's exact test. quantitative parameters analyzed Kruskal-Wallis rank sum successfully all TOF. Right characterized (a) greater SVC/IVC during diastole than systole, (b) increased vortical RA RV diastole, (c) helical or features PA's. main index, acceleration statistically significant. Whole enables detection both abnormal patterns, which may allow for comprehensive to evaluate interdependencies post-surgically altered geometries hemodynamics.

参考文章(34)
Elisabeth Bédard, Karen P. McCarthy, Konstantinos Dimopoulos, Georgios Giannakoulas, Michael A. Gatzoulis, Siew Yen Ho, Structural abnormalities of the pulmonary trunk in tetralogy of Fallot and potential clinical implications: a morphological study Journal of the American College of Cardiology. ,vol. 54, pp. 1883- 1890 ,(2009) , 10.1016/J.JACC.2009.06.040
Philip J. Kilner, Guang-Zhong Yang, A. John Wilkes, Raad H. Mohiaddin, David N. Firmin, Magdi H. Yacoub, Asymmetric redirection of flow through the heart Nature. ,vol. 404, pp. 759- 761 ,(2000) , 10.1038/35008075
Kevin M. Johnson, Darren P. Lum, Patrick A. Turski, Walter F. Block, Charles A. Mistretta, Oliver Wieben, Improved 3D Phase Contrast MRI with Off-resonance Corrected Dual Echo VIPR Magnetic Resonance in Medicine. ,vol. 60, pp. 1329- 1336 ,(2008) , 10.1002/MRM.21763
Michael Markl, Mary T Draney, Michael D Hope, Jonathan M Levin, Frandics P Chan, Marcus T Alley, Norbert J Pelc, Robert J Herfkens, Time-resolved 3-dimensional velocity mapping in the thoracic aorta: visualization of 3-directional blood flow patterns in healthy volunteers and patients. Journal of Computer Assisted Tomography. ,vol. 28, pp. 459- 468 ,(2004) , 10.1097/00004728-200407000-00005
Gautam K. Singh, S.Bruce Greenberg, Yong S. Yap, David P. Delany, Barry R. Keeton, James L. Monro, Right ventricular function and exercise performance late after primary repair of tetralogy of Fallot with the transannular patch in infancy. American Journal of Cardiology. ,vol. 81, pp. 1378- 1382 ,(1998) , 10.1016/S0002-9149(98)00171-4
Balram Airan, Gurpreet S. Gulati, Shyam Sunder Kothari, Anita Saxena, Mani Kalaivani, Panangipalli Venugopal, Ujjwal K. Chowdhury, Kizakke K. Pradeep, Chetan D. Patel, Rajvir Singh, A. Sampath Kumar, Noninvasive assessment of repaired tetralogy of Fallot by magnetic resonance imaging and dynamic radionuclide studies. The Annals of Thoracic Surgery. ,vol. 81, pp. 1436- 1442 ,(2006) , 10.1016/J.ATHORACSUR.2005.08.081
Willem A. Helbing, R. Andre Niezen, Saskia Le Cessie, Rob J. Van Der Geest, Jaap Ottenkamp, Albert De Roos, Right Ventricular Diastolic Function in Children With Pulmonary Regurgitation After Repair of Tetralogy of Fallot: Volumetric Evaluation by Magnetic Resonance Velocity Mapping Journal of the American College of Cardiology. ,vol. 28, pp. 1827- 1835 ,(1996) , 10.1016/S0735-1097(96)00387-7
Christopher P. Appleton, Liv K. Hatle, Richard L. Popp, Superior vena cava and hepatic vein Doppler echocardiography in healthy adults Journal of the American College of Cardiology. ,vol. 10, pp. 1032- 1039 ,(1987) , 10.1016/S0735-1097(87)80343-1
Tal Geva, Bryan M Sandweiss, Kimberlee Gauvreau, James E Lock, Andrew J Powell, None, Factors associated with impaired clinical status in long-term survivors of tetralogy of Fallot repair evaluated by magnetic resonance imaging Journal of the American College of Cardiology. ,vol. 43, pp. 1068- 1074 ,(2004) , 10.1016/J.JACC.2003.10.045
Alex Frydrychowicz, Alexander Berger, Maximilan F. Russe, Aurélien F. Stalder, Andreas Harloff, Sven Dittrich, Jürgen Hennig, Mathias Langer, Michael Markl, Time-resolved magnetic resonance angiography and flow-sensitive 4-dimensional magnetic resonance imaging at 3 Tesla for blood flow and wall shear stress analysis The Journal of Thoracic and Cardiovascular Surgery. ,vol. 136, pp. 400- 407 ,(2008) , 10.1016/J.JTCVS.2008.02.062