Studies on functionalizing and grafting to poly(ether-urethanes)

摘要: Abstract The grafting of hydrophilic polymers to the surface a poly(ether-urethane) substrate is particular interest in design materials for biomedical applications. We are opinion that none currently-favoured methods satisfactory preparation well-characterized linear grafts this kind. In paper some general applicability chemical poly(ether-urethanes) described. These rely on generating free-radical sites nitrogen atoms polymer by interaction N -chlorinated or -brominated with suitable transition metal derivative. Bulk and experimental arterial prostheses constructed from fine (1 μ) filaments have been used as substrates. sensitive many monomers grafting, which strong swelling agents even solvents. It therefore essential use mild conditions throughout minimize damage specimens. systems accompanied detachment layers reaction mixture (by extraction and/or solubilization). This phenomenon, has an important influence nature final surface, vitiates estimation true extent weight changes. radio-labelled investigate degree relative importance solubilization.