An Historical Perspective on How Advances in Microscopic Imaging Contributed to Understanding the Leishmania Spp. and Trypanosoma cruzi Host-Parasite Relationship
作者： P. T. V. Florentino , F. Real , A. Bonfim-Melo , C. M. Orikaza , E. R. Ferreira
DOI: 10.1155/2014/565291
关键词:
摘要: The literature has identified complex aspects of intracellular host-parasite relationships, which require systematic, nonreductionist approaches and spatial/temporal information. Increasing integrating temporal spatial dimensions in host cell imaging have contributed to elucidating several conceptual gaps the biology parasites. To access investigate emergent dynamic events, it is mandatory follow them context living cells organs, constructing scientific images with integrated high quality spatiotemporal data. This review discusses examples how advances microscopy challenged established models life cycles Leishmania spp. Trypanosoma cruzi protozoan
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