Methods for identifying androgen receptor splice variants in subjects having castration resistant prostate cancer
作者： Jun Luo , Emmanuel S. Antaonarakis , Changxue Lu
DOI:
关键词:
摘要: Methods of the present disclosure provide for detection mutations and splice variants androgen receptor using a non-invasive approach, RNAseq, examining circulating tumor ceils.
lens.org参考文章(176)
R. W. Roberts, J. W. Szostak, RNA-peptide fusions for the in vitro selection of peptides and proteins Proceedings of the National Academy of Sciences of the United States of America. ,vol. 94, pp. 12297- 12302 ,(1997) , 10.1073/PNAS.94.23.12297
Jocelyn Céraline, Marion D. Cruchant, Eva Erdmann, Philippe Erbs, Jean-Emmanuel Kurtz, Brigitte Duclos, Didier Jacqmin, Dominique Chopin, Jean-Pierre Bergerat, Constitutive activation of the androgen receptor by a point mutation in the hinge region: a new mechanism for androgen-independent growth in prostate cancer. International Journal of Cancer. ,vol. 108, pp. 152- 157 ,(2004) , 10.1002/IJC.11404
Martine Verhoeyen, Lutz Riechmann, Engineering of antibodies BioEssays. ,vol. 8, pp. 74- 78 ,(1988) , 10.1002/BIES.950080207
M. Schena, D. Shalon, R. Heller, A. Chai, P. O. Brown, R. W. Davis, Parallel human genome analysis: microarray-based expression monitoring of 1000 genes Proceedings of the National Academy of Sciences of the United States of America. ,vol. 93, pp. 10614- 10619 ,(1996) , 10.1073/PNAS.93.20.10614
S.P.M. Crouch, R. Kozlowski, K.J. Slater, J. Fletcher, The use of ATP bioluminescence as a measure of cell proliferation and cytotoxicity Journal of Immunological Methods. ,vol. 160, pp. 81- 88 ,(1993) , 10.1016/0022-1759(93)90011-U
A.O Brinkmann, L.J Blok, P.E de Ruiter, P Doesburg, K Steketee, C.A Berrevoets, J Trapman, Mechanisms of androgen receptor activation and function The Journal of Steroid Biochemistry and Molecular Biology. ,vol. 69, pp. 307- 313 ,(1999) , 10.1016/S0960-0760(99)00049-7
M. Chee, R. Yang, E. Hubbell, A. Berno, X. C. Huang, D. Stern, J. Winkler, D. J. Lockhart, M. S. Morris, S. P. A. Fodor, Accessing Genetic Information with High-Density DNA Arrays Science. ,vol. 274, pp. 610- 614 ,(1996) , 10.1126/SCIENCE.274.5287.610
Michael J. Kozal, Nila Shah, Naiping Shen, Robert Yang, Raymond Fucini, Thomas C. Merigan, Douglas D. Richman, Don Morris, Earl Hubbell, Mark Chee, Thomas R. Gingeras, Extensive polymorphisms observed in HIV–1 clade B protease gene using high–density oligonucleotide arrays Nature Medicine. ,vol. 2, pp. 753- 759 ,(1996) , 10.1038/NM0796-753
YOO-JOUNG KO, GAYATHRI R. DEVI, CARLA A. LONDON, ANTHONY KAYAS, MURALIMOHAN T. REDDY, PATRICK L. IVERSEN, GLENN J. BUBLEY, STEVEN P. BALK, ANDROGEN RECEPTOR DOWN-REGULATION IN PROSTATE CANCER WITH PHOSPHORODIAMIDATE MORPHOLINO ANTISENSE OLIGOMERS The Journal of Urology. ,vol. 172, pp. 1140- 1144 ,(2004) , 10.1097/01.JU.0000134698.87862.E6
Monika Jagla, Marie Fève, Pascal Kessler, Gaëlle Lapouge, Eva Erdmann, Sebastian Serra, Jean-Pierre Bergerat, Jocelyn Céraline, A splicing variant of the androgen receptor detected in a metastatic prostate cancer exhibits exclusively cytoplasmic actions. Endocrinology. ,vol. 148, pp. 4334- 4343 ,(2007) , 10.1210/EN.2007-0446