A gene family for acidic ribosomal proteins in Schizosaccharomyces pombe: two essential and two nonessential genes.

作者: M Beltrame , M E Bianchi

DOI: 10.1128/MCB.10.5.2341

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摘要: We have cloned the genes for small acidic ribosomal proteins (A-proteins) of fission yeast Schizosaccharomyces pombe. S. pombe contains four transcribed A-proteins per haploid genome, as is case Saccharomyces cerevisiae. In contrast, multicellular eucaryotes contain two genome. The pombe, besides sharing a high overall similarity, form couples nearly identical sequences. Their corresponding very conserved structure and are to similar level. Surprisingly, each couple coding proteins, one essential cell growth, whereas other not. suggest that unequal importance survival related their physical organization in 60S subunits.

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