Management of non-small cell lung cancer in the era of personalized medicine

摘要: Despite major advances in the molecular definition of disease, screening and therapy, non-small cell lung cancer (NSCLC) is still characterized by a disappointing overall survival, depending on subtype tumor stage. To address this challenge, last years therapeutic algorithm NSCLC has become much more complex articulated, with different kinds drugs, including chemotherapy, targeted-based agents, angiogenesis inhibitors immunotherapy, multiple lines treatments, for patients squamous non-squamous hystology, EGFR mutation ALK rearrangement. This short viewpoint describes emerging strategies management NSCLC, indicating how personalized approach, specific multidisciplinary involvement, implies process that starts early detection includes surgery systemic therapy.