Inhibitors of mitochondrial complex I attenuate the accumulation of hypoxia-inducible factor-1 during hypoxia in Hep3B cells

作者: Faton H Agani , Paola Pichiule , Juan Carlos Chavez , Joseph C LaManna

DOI: 10.1016/S1095-6433(01)00535-9

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摘要: … We found, consistent with our previous observations in Cath.a and PC12 cells, that rotenone and MPP + attenuated the HIF-1α hypoxic response. Thus, it can be concluded that an intact…

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