Sodium hyaluronate eyedrops enhance tear film stability.

摘要: Sodium hyaluronate eyedrops can relieve various dry eye symptoms by prolonging the stability of precorneal tear film. To determine most effective concentration sodium hyaluronate, we studied concentration-dependent effects on film breakup time (BUT) in 12 volunteers. These subjects had a BUT 10 seconds or less and low volume determined with phenol red thread test. They received four different concentrations (0, 0.05, 0.1 0.3%). was measured noninvasively using non-contact specular microscope before eyedrop instillation again after 5, 15, 30, 60, 120 180 minutes. The period prolonged significantly 0.1% 0.3% at all measurement times (P < 0.05), while eyes treated 0% 0.05% showed no significant prolongation any times. findings this study confirm that least is required to delay