New drug treatments for HIV infection and AIDS. A review following the Seventh International Conference on AIDS, Florence 16-21 June 1991.
作者： GR Venning , GM Scott
DOI: 10.1111/J.1365-2125.1992.TB04051.X
关键词:
摘要: 1. OBJECTIVE--To evaluate the status of clinical development zidovudine and new drugs for treatment Human Immunodeficiency Virus (HIV) infections. 2. METHOD--A critical review trial reports assessment design methodology therapeutic trials. Evaluation being tested specific difficulties in testing AIDS. 3. CONCLUSIONS--Drugs are a unique climate public opinion characterised by (1) fast track criteria regulatory approval (2) parallel (compassionate release) before adequate determination safety efficacy (3) resistance to use placebos controlled
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