Anaplastic lymphoma kinase (ALK) inhibitors in the treatment of ALK-driven lung cancers.

作者: Robert Roskoski

DOI: 10.1016/J.PHRS.2017.01.007

关键词:

摘要: … Moreover, nearly two dozen ALK activating mutations are … ALK-fusion proteins, particularly in non-small cell lung cancer, has fostered considerable interest in the development of ALK …

参考文章(80)
Fujimoto J, Shiota M, Mori S, Yamamoto T, Satoh H, Semba T, Hyperphosphorylation of a Novel 80 kDa Protein-Tyrosine Kinase Similar to Ltk in a Human Ki-1 Lymphoma Cell Line, AMS3 Oncogene. ,vol. 9, pp. 1567- 1574 ,(1994)
Emer O. Hanrahan, Bonnie Glisson, Small Cell Carcinoma of the Lung Humana Press, Totowa, NJ. pp. 395- 434 ,(2010) , 10.1007/978-1-60761-524-8_16
Helen Y. Zou, Luc Friboulet, David P. Kodack, Lars D. Engstrom, Qiuhua Li, Melissa West, Ruth W. Tang, Hui Wang, Konstantinos Tsaparikos, Jinwei Wang, Sergei Timofeevski, Ryohei Katayama, Dac M. Dinh, Hieu Lam, Justine L. Lam, Shinji Yamazaki, Wenyue Hu, Bhushankumar Patel, Divya Bezwada, Rosa L. Frias, Eugene Lifshits, Sidra Mahmood, Justin F. Gainor, Timothy Affolter, Patrick B. Lappin, Hovhannes Gukasyan, Nathan Lee, Shibing Deng, Rakesh K. Jain, Ted W. Johnson, Alice T. Shaw, Valeria R. Fantin, Tod Smeal, PF-06463922, an ALK/ROS1 Inhibitor, Overcomes Resistance to First and Second Generation ALK Inhibitors in Preclinical Models. Cancer Cell. ,vol. 28, pp. 70- 81 ,(2015) , 10.1016/J.CCELL.2015.05.010
Svetlana Favelyukis, Jeffrey H. Till, Stevan R. Hubbard, W. Todd Miller, Structure and autoregulation of the insulin-like growth factor 1 receptor kinase. Nature Structural & Molecular Biology. ,vol. 8, pp. 1058- 1063 ,(2001) , 10.1038/NSB721
Susan S. Taylor, Alexandr P. Kornev, Protein kinases: evolution of dynamic regulatory proteins Trends in Biochemical Sciences. ,vol. 36, pp. 65- 77 ,(2011) , 10.1016/J.TIBS.2010.09.006
Diletta Fontana, Monica Ceccon, Carlo Gambacorti-Passerini, Luca Mologni, Activity of second-generation ALK inhibitors against crizotinib-resistant mutants in an NPM-ALK model compared to EML4-ALK Cancer Medicine. ,vol. 4, pp. 953- 965 ,(2015) , 10.1002/CAM4.413