Utilization of pyrene and benzoate in Mycobacterium isolate KMS is regulated differentially by catabolic repression.

摘要: The soil isolate, Mycobacterium sp. strain KMS, utilizes an array of carbon compounds including the aromatics benzoate and pyrene as sole sources. Growth on induced both chromosomal plasmid nidA genes encoding ring-hydroxylating dioxygenase α-subunits for oxidation. Diauxic growth occurred when KMS was cultured with plus either acetate, succinate, fructose, or expression only detected in second slower log-phase period. Potential cAMP-CRP binding sites exist within promoter region indicating that may be involved catabolite repression utilization. When there no diauxic growth. Also fructose succinate acetate. Expression a benA gene, α-subunit initiation oxidation, cells from benzoate-mixed substrate cultures at same level were alone. These findings suggested but not isolate KMS. differences help microbe exploit varied sources available rhizosphere environments.