What can HIV vaccine trials teach us about future HIV vaccine dissemination

摘要: This investigation explored commonalities and differences in barriers motivators to HIV vaccine trial participation acceptability of future U.S. Food Drug Administration (FDA)-approved vaccines order identify implications clinical trials for dissemination. Fifteen focus groups were conducted with 157 predominately ethnic minority low income participants recruited using venue-based sampling Los Angeles. Data analyzed narrative thematic analysis. Barriers common across willingness participate (WTP) (e.g., concerns about vaccine-induced infection, false-positives, side effects, efficacy, mistrust stigma) suggest present significant opportunities develop evaluate empirically based interventions support specific duration protection, cross-clade cost access) also indicate the need formative research focused specifically on Protection motivation, WTP acceptability, highlights provide prevention counseling education trials, which may form basis evidence-informed preventive be launched tandem dissemination partial efficacy vaccines.