Monoclonal antibodies against hepatitis A virus.

摘要: Three monoclonal antibodies (K2-4F2, K3-2F2, and K3-4C8) of the immunoglobulin G2a class were raised against hepatitis A virus. The specificity these was confirmed by immune electron microscopy, solid-phase radioimmunoassay, in vitro neutralization cell culture. Binding studies suggested that they all recognize closely related antigenic determinants. These should prove to be great value as diagnostic research reagents.