Intractable epistaxis and systemic lupus: High-dose intravenous pulse steroids

摘要: Abstract Importance Epistaxis is most commonly an easily treated ENT entity with a relatively simple algorithm. Occasionally, however, it encountered as devastating disease process that can humble the otolaryngologist. In setting of comorbidities exacerbate bleeding, in this case vasculitis due to systemic lupus erythematosus (SLE), epistaxis be life-threatening and refractory conservative management. Observations This report describes hospital course patient severe SLE intractable epistaxis. We discuss classic management options for offer novel treatment option patients SLE-related vasculitides—goal-directed medical therapy high-dose intravenous pulse steroid therapy. Conclusions Relevance To our knowledge, not only first description targeted SLE, but also serves augment traditional algorithm addition goal-directed therapy—control through demonstrated 6 mg dexamethasone given every 6 hours highly effective controlling uncontrolled SLE. The presumed mechanism control associated vasculitides.