Secreted aspartic protease 2 of Candida albicans inactivates factor H and the macrophage factor H-receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18).
作者： Eliška Svoboda , Andrea E. Schneider , Noémi Sándor , Ulrich Lermann , Peter Staib
DOI: 10.1016/J.IMLET.2015.08.009
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摘要: … increase the production of lactoferrin and reactive oxygen species by these host cells [23]. … CR3 can also bind directly to fungal surface moieties, such as beta-glucan and pH-regulated …
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