Gut microbial short-chain fatty acids-mediated olfactory receptor 78 stimulation promotes anorexigenic gut hormone peptide YY secretion in mice.

作者: Ikuo Kimura , Ikuo Kimura , Ikuo Kimura , Akari Nishida , Junki Miyamoto

DOI: 10.1016/J.BBRC.2021.03.167

关键词:

摘要: … sympathetic activation and secretion of the anorexigenic gut hormone peptide YY (PYY) [15,16]. In … tumor cell line (STC-1) as a model of enteroendocrine cells and Olfr78-deficient mice. …

参考文章(26)
Emanuel E. Canfora, Johan W. Jocken, Ellen E. Blaak, Short-chain Fatty Acids in Control of Body Weight and Insulin Sensitivity Nature Reviews Endocrinology. ,vol. 11, pp. 577- 591 ,(2015) , 10.1038/NRENDO.2015.128
Harry J. Flint, Edward A. Bayer, Marco T. Rincon, Raphael Lamed, Bryan A. White, Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis Nature Reviews Microbiology. ,vol. 6, pp. 121- 131 ,(2008) , 10.1038/NRMICRO1817
Nagendra Singh, Ashish Gurav, Sathish Sivaprakasam, Evan Brady, Ravi Padia, Huidong Shi, Muthusamy Thangaraju, Puttur D. Prasad, Santhakumar Manicassamy, David H. Munn, Jeffrey R. Lee, Stefan Offermanns, Vadivel Ganapathy, Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis Immunity. ,vol. 40, pp. 128- 139 ,(2014) , 10.1016/J.IMMUNI.2013.12.007
Kendle M Maslowski, Charles R Mackay, Diet, gut microbiota and immune responses Nature Immunology. ,vol. 12, pp. 5- 9 ,(2011) , 10.1038/NI0111-5
Jennifer L. Pluznick, Ryan J. Protzko, Haykanush Gevorgyan, Zita Peterlin, Arnold Sipos, Jinah Han, Isabelle Brunet, La-Xiang Wan, Federico Rey, Tong Wang, Stuart J. Firestein, Masashi Yanagisawa, Jeffrey I. Gordon, Anne Eichmann, Janos Peti-Peterdi, Michael J. Caplan, Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation Proceedings of the National Academy of Sciences of the United States of America. ,vol. 110, pp. 4410- 4415 ,(2013) , 10.1073/PNAS.1215927110
Won-Jae Lee, Koji Hase, Gut microbiota–generated metabolites in animal health and disease Nature Chemical Biology. ,vol. 10, pp. 416- 424 ,(2014) , 10.1038/NCHEMBIO.1535
Thomas Bozza, Anne Vassalli, Stefan Fuss, Jing-Ji Zhang, Brian Weiland, Rodrigo Pacifico, Paul Feinstein, Peter Mombaerts, Mapping of Class I and Class II Odorant Receptors to Glomerular Domains by Two Distinct Types of Olfactory Sensory Neurons in the Mouse Neuron. ,vol. 61, pp. 220- 233 ,(2009) , 10.1016/J.NEURON.2008.11.010
Ikuo Kimura, Kentaro Ozawa, Daisuke Inoue, Takeshi Imamura, Kumi Kimura, Takeshi Maeda, Kazuya Terasawa, Daiji Kashihara, Kanako Hirano, Taeko Tani, Tomoyuki Takahashi, Satoshi Miyauchi, Go Shioi, Hiroshi Inoue, Gozoh Tsujimoto, The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43 Nature Communications. ,vol. 4, pp. 1829- 1829 ,(2013) , 10.1038/NCOMMS2852
Joerg Fleischer, Rosolino Bumbalo, Verena Bautze, Joerg Strotmann, Heinz Breer, Expression of odorant receptor Olfr78 in enteroendocrine cells of the colon Cell and Tissue Research. ,vol. 361, pp. 697- 710 ,(2015) , 10.1007/S00441-015-2165-0
Vanitha Bala, Senthilkumar Rajagopal, Divya P. Kumar, Ancy D. Nalli, Sunila Mahavadi, Arun J. Sanyal, John R. Grider, Karnam S. Murthy, Release of GLP-1 and PYY in response to the activation of G protein-coupled bile acid receptor TGR5 is mediated by Epac/PLC-ε pathway and modulated by endogenous H2S Frontiers in Physiology. ,vol. 5, pp. 420- 420 ,(2014) , 10.3389/FPHYS.2014.00420