The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43
作者： Ikuo Kimura , Kentaro Ozawa , Daisuke Inoue , Takeshi Imamura , Kumi Kimura
DOI: 10.1038/NCOMMS2852
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摘要: … To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we …
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cyberleninka.org参考文章(51)
Robert L. Kortum, Diane L. Costanzo, Jamie Haferbier, Steven J. Schreiner, Gina L. Razidlo, Ming-Hoi Wu, Deanna J. Volle, Toshiyuki Mori, Hiroshi Sakaue, Nina V. Chaika, Oleg V. Chaika, Robert E. Lewis, The Molecular Scaffold Kinase Suppressor of Ras 1 (KSR1) Regulates Adipogenesis Molecular and Cellular Biology. ,vol. 25, pp. 7592- 7604 ,(2005) , 10.1128/MCB.25.17.7592-7604.2005
Emmanuel Le Poul, Cécile Loison, Sofie Struyf, Jean-Yves Springael, Vincent Lannoy, Marie-Eve Decobecq, Stéphane Brezillon, Vincent Dupriez, Gilbert Vassart, Jo Van Damme, Marc Parmentier, Michel Detheux, Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. Journal of Biological Chemistry. ,vol. 278, pp. 25481- 25489 ,(2003) , 10.1074/JBC.M301403200
Kendle M Maslowski, Angelica T Vieira, Aylwin Ng, Jan Kranich, Frederic Sierro, Di Yu, Heidi C Schilter, Michael S Rolph, Fabienne Mackay, David Artis, Ramnik J Xavier, Mauro M Teixeira, Charles R Mackay, None, Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43 Nature. ,vol. 461, pp. 1282- 1286 ,(2009) , 10.1038/NATURE08530
Peter J. Turnbaugh, Ruth E. Ley, Michael A. Mahowald, Vincent Magrini, Elaine R. Mardis, Jeffrey I. Gordon, An obesity-associated gut microbiome with increased capacity for energy harvest Nature. ,vol. 444, pp. 1027- 1031 ,(2006) , 10.1038/NATURE05414
G. Tolhurst, H. Heffron, Y. S. Lam, H. E. Parker, A. M. Habib, E. Diakogiannaki, J. Cameron, J. Grosse, F. Reimann, F. M. Gribble, Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein–Coupled Receptor FFAR2 Diabetes. ,vol. 61, pp. 364- 371 ,(2012) , 10.2337/DB11-1019
Brighenti F, Royall D, Wolever Tm, Jenkins Dj, Jenkins Al, Effect of rectal infusion of short chain fatty acids in human subjects. The American Journal of Gastroenterology. ,vol. 84, pp. 1027- ,(1989)
Q Zhou, G Li, XY Deng, XB He, LJ Chen, C Wu, Y Shi, KP Wu, LJ Mei, JX Lu, NM Zhou, Activated human hydroxy-carboxylic acid receptor-3 signals to MAP kinase cascades via the PLC-dependent PKC and MMP-mediated EGFR pathways British Journal of Pharmacology. ,vol. 166, pp. 1756- 1773 ,(2012) , 10.1111/J.1476-5381.2012.01875.X
David L. Topping, Peter M. Clifton, Short-Chain Fatty Acids and Human Colonic Function: Roles of Resistant Starch and Nonstarch Polysaccharides Physiological Reviews. ,vol. 81, pp. 1031- 1064 ,(2001) , 10.1152/PHYSREV.2001.81.3.1031
M Denise Robertson, Alex S Bickerton, A Louise Dennis, Hubert Vidal, Keith N Frayn, Insulin-sensitizing effects of dietary resistant starch and effects on skeletal muscle and adipose tissue metabolism The American Journal of Clinical Nutrition. ,vol. 82, pp. 559- 567 ,(2005) , 10.1093/AJCN.82.3.559
Torgeir Høverstad, Tore Midtvedt, Short-Chain Fatty Acids in Germfree Mice and Rats Journal of Nutrition. ,vol. 116, pp. 1772- 1776 ,(1986) , 10.1093/JN/116.9.1772