Estrogen receptor and endocrine responsiveness in Japanese versus American breast cancer patients.

作者: W. L. McGuire , S. Kobayashi , H. Sugano , Y. Nomura , K. Matsumoto

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摘要: We have compared the incidence of estrogen receptor (ER) in breast tumors and its clinical correlation with responses to endocrine therapies Japanese American patients. There was no between tumor histopathoogy presence ER, ER values primary metastatic lesions from same patients were similar most cases. low high plasma estradiol levels had identical incidences ER-positive tumors. The response therapy is The higher postmenopausal both lesions. It possible that reported increase lymphocyte infiltration may explain this difference. 5-year survival advantage cancer cannot be explained by differences two populations for advanced disease.

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