Specific estrogen-receptors in the neoplastic and lactating mammary gland of the rat☆
作者： James L. Wittliff , David G. Gardner , William L. Battema , Peter J. Gilbert
DOI: 10.1016/0006-291X(72)90352-X
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摘要: Abstract Specific receptors of 3 H-estradiol-17β were demonstrated by a sucrose gradient assay cytosols from the lactating mammary gland and R3230AC adenocarcinoma rat. These estrogen receptors, each which sedimented at approximately 8S, exhibited similar dissociation constants (K d ∼1×10 −9 M) steroid binding specificities. Ovariectomy host had no apparent effect on number sites/mg protein in tumor.
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