作者: Karin C. Huth , Martina Quirling , Stefanie Lenzke , Ekaterini Paschos , Klaus Kamereck
DOI: 10.1111/J.1600-0722.2011.00825.X
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摘要: Ozone has been proposed as an adjunct antiseptic in periodontitis therapy. The aim of this study was to investigate the antimicrobial effectiveness gaseous/aqueous ozone, comparison with that established chlorhexidine digluconate (CHX), against periodontal microorganisms. Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, and Parvimonas micra planktonic or biofilm cultures were exposed, for 1 min, gaseous aqueous CHX, phosphate-buffered saline (control). None agents able substantially reduce A. actinomycetemcomitans count cultures. In contrast, P. T. could be eliminated by 2% CHX ozone gas at 53 gm(-3) . Significantly greater effects observed than biofilm-associated bacteria. rate killing influenced species bacteria, type concentration agent. There no significant differences (20 μg ml(-1) ) (≥ 4 compared but they more effective 0.2% CHX. Therefore, high-concentrated merit further investigation antiseptics A safe system applying into pocket avoids inhalation still needs developed.