Effectiveness of ozone against periodontal pathogenic microorganisms

作者: Karin C. Huth , Martina Quirling , Stefanie Lenzke , Ekaterini Paschos , Klaus Kamereck

DOI: 10.1111/J.1600-0722.2011.00825.X

关键词:

摘要: Ozone has been proposed as an adjunct antiseptic in periodontitis therapy. The aim of this study was to investigate the antimicrobial effectiveness gaseous/aqueous ozone, comparison with that established chlorhexidine digluconate (CHX), against periodontal microorganisms. Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, and Parvimonas micra planktonic or biofilm cultures were exposed, for 1 min, gaseous aqueous CHX, phosphate-buffered saline (control). None agents able substantially reduce A. actinomycetemcomitans count cultures. In contrast, P. T. could be eliminated by 2% CHX ozone gas at 53 gm(-3) . Significantly greater effects observed than biofilm-associated bacteria. rate killing influenced species bacteria, type concentration agent. There no significant differences (20 μg ml(-1) ) (≥ 4 compared but they more effective 0.2% CHX. Therefore, high-concentrated merit further investigation antiseptics A safe system applying into pocket avoids inhalation still needs developed.

参考文章(37)
Carlos Goes Nogales, Patricia Helena Ferrari, Efraim Olszawer Kantorovich, José Luiz Lage-Marques, Ozone therapy in medicine and dentistry. The journal of contemporary dental practice. ,vol. 9, pp. 75- 84 ,(2008) , 10.5005/JCDP-9-4-75
Panagiota Paraskeva, Nigel J. D. Graham, Ozonation of municipal wastewater effluents. Water Environment Research. ,vol. 74, pp. 569- 581 ,(2002) , 10.2175/106143002X140387
Petrukhina Nb, Voinov Pa, Bezrukova, Experience in medical ozone use for root canal treatment Stomatologiia. ,vol. 84, pp. 20- 22 ,(2005)
M.P. RIGGIO, A. LENNON, A. SMITH, Detection of peptostreptococcus micros DNA in clinical samples by PCR. Journal of Medical Microbiology. ,vol. 50, pp. 249- 254 ,(2001) , 10.1099/0022-1317-50-3-249
C. Bassetti, A. Kallenberger, Influence of chlorhexidine rinsing on the healing of oral mucosa and osseous lesions. Journal of Clinical Periodontology. ,vol. 7, pp. 443- 456 ,(1980) , 10.1111/J.1600-051X.1980.TB02151.X
T. Honda, H. Domon, T. Okui, K. Kajita, R. Amanuma, K. Yamazaki, Balance of inflammatory response in stable gingivitis and progressive periodontitis lesions. Clinical and Experimental Immunology. ,vol. 144, pp. 35- 40 ,(2006) , 10.1111/J.1365-2249.2006.03028.X
Knud Sehested, Hanne Corfitzen, Jerzy Holcman, Christian H. Fischer, Edwin J. Hart, The primary reaction in the decomposition of ozone in acidic aqueous solutions Environmental Science & Technology. ,vol. 25, pp. 1589- 1596 ,(1991) , 10.1021/ES00021A010
Angelo J. Mariotti, Deborah A.H. Rumpf, Chlorhexidine‐Induced Changes to Human Gingival Fibroblast Collagen and Non‐Collagen Protein Production Journal of Periodontology. ,vol. 70, pp. 1443- 1448 ,(1999) , 10.1902/JOP.1999.70.12.1443
P. Gilbert, J. Das, I. Foley, Biofilm Susceptibility to Antimicrobials Advances in Dental Research. ,vol. 11, pp. 160- 167 ,(1997) , 10.1177/08959374970110010701