Tuberculosis Compositions And Methods Of Using The Same

作者: Barry Walker , Nathalie Cadieux , Michele Stone , Ravi Anantha , Thomas G. Evans

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摘要: The present disclosure provides fusion proteins comprising Mycobacterium tuberculosis (Mtb) antigens, nucleic acid molecules encoding the same, vectors molecules, compositions and methods of eliciting an immune response against tuberculosis.

参考文章(16)
哲哉 野阪, 福村 正之, 光雄 河野, 康宏 保富, Nebulizable tuberculosis vaccine for transnasal administration comprising paramyxovirus vector ,(2010)
Geneviève Inchaupse, Charles Antoine Coupet, Marie Gouanvic, Nathalie Silvestre, Emmanuel Tupin, Jean-Baptiste Marchand, Cécile Beny, Romain Micol, Mycobacterial antigen vaccine ,(2013)
Jerald C. Sadoff, Naomi Ariel, Ronggai Sun, Rosemary Chang, John Fulkerson, Anat Zvi, Avigdor Shafferman, Recombinant BCG tuberculosis vaccine designed to elicit immune responses to Mycobacterium tuberculosis in all physiological stages of infection and disease ,(2007)
James Brown, Dennis Murphy, Anne-Marie Gelinas, Normand Blais, Pascal Mettens, Modified tuberculosis antigens ,(2011)
Susanna Commandeur, Susan J.F. van den Eeden, Karin Dijkman, Simon O. Clark, Krista E. van Meijgaarden, Louis Wilson, Kees L.M.C. Franken, Ann Williams, Dennis Christensen, Tom H.M. Ottenhoff, Annemieke Geluk, The in vivo expressed Mycobacterium tuberculosis (IVE-TB) antigen Rv2034 induces CD4⁺ T-cells that protect against pulmonary infection in HLA-DR transgenic mice and guinea pigs. Vaccine. ,vol. 32, pp. 3580- 3588 ,(2014) , 10.1016/J.VACCINE.2014.05.005
K. A. Millington, S. M. Fortune, J. Low, A. Garces, S. M. Hingley-Wilson, M. Wickremasinghe, O. M. Kon, A. Lalvani, Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection Proceedings of the National Academy of Sciences of the United States of America. ,vol. 108, pp. 5730- 5735 ,(2011) , 10.1073/PNAS.1015153108
Stefan H.E. Kaufmann, Tuberculosis vaccines: time to think about the next generation. Seminars in Immunology. ,vol. 25, pp. 172- 181 ,(2013) , 10.1016/J.SMIM.2013.04.006