作者: 哲哉 野阪 , 福村 正之 , 光雄 河野 , 康宏 保富
DOI:
关键词: Virology 、 Gene 、 Tuberculosis 、 Vector (molecular biology) 、 Equivalent function 、 Mycobacterium 、 Tuberculosis vaccines 、 Biology 、 Mycobacterium bovis
摘要: Disclosed is a nebulizable vaccine for transnasal administration, which has high prophylactic effect on human tuberculosis, particular adult tuberculosis. The tuberculosis administration comprises paramyxovirus gene (particularly rhPIV2) having, integrated therein, encoding an α-antigen derived from acid-fast bacterium (e.g., Mycobacterium kansaii or bovis BCG), analogue of the gene, variant equivalent function to that gene.