PHARMACEUTICAL COMPOSITION USING PARAINFLUENZA VIRUS TYPE 2

作者: Yasutomi Yasuhiro , Kono Mitsuo

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摘要: PROBLEM TO BE SOLVED: To provide a pharmaceutical composition, etc., comprising an α antigen, integrated into PIV2 (parainfluenza virus type 2) and usable for therapy/prophylaxis of allergic diseases. SOLUTION: The composition is obtained by integrating gene encoding the antigen derived from acid-fast bacterium (e.g. Mycobacterium kansasii) (antigen 85 complex constituent protein 85B), analog thereof (85A or 85C, etc.) mutant having similar actions thereto in which M deficient. COPYRIGHT: (C)2008,JPO&INPIT

参考文章(2)
Brian R. Murphy, Peter L. Collins, Anna P. Durbin, Mario H. Skiadopoulos, Tao Tao, Alexander C. Schmidt, USE OF RECOMBINANT PARAINFLUENZA VIRUSES (PIVs) AS VECTORS TO PROTECT AGAINST INFECTION AND DISEASE CAUSED BY PIV AND OTHER HUMAN PATHOGENS ,(2000)
Yasuhiro Yasutomi, Hitoshi Mizutani, Novel medicinal use of aplpha antigen or alpha antigen gene ,(2002)