In vitro antibacterial activity of crude extracts of 9 selected medicinal plants against UTI causing MDR bacteria

摘要: Abstract Urinary tract infection (UTI) has become a more grievous problem today, due to multidrug resistance of infecting Gram-positive (GP) and Gram-negative (GN) bacteria, sometimes even with multiple infections. This study examines effectivity 9 tropical flowering plants ( Anogeissus acuminata , Azadirachta indica, Bauhinia variegata Boerhaavia diffusa Punica granatum Soymida febrifuga Terminalia chebula Tinospora cordifolia Tribulus terrestris ) for possible use as source antimicrobials resistant (MDR) along main-stream antibiotics. Pathogenic bacteria were isolated from urine samples patients attending admitted in the hospital. Antibiograms 11 (GPs, Enterococcus faecalis Staphylococcus aureus ; GNs, Acinetobacter baumannii Citrobacter freundii Enterobacter aerogenes Escherichia coli Klebsiella oxytoca pneumoniae Proteus mirabilis vulgaris Pseudomonas aeruginosa ascertained by disc-diffusion method, antibacterial plant extracts was monitored agar-well diffusion method. Isolated floridly MDR most antibiotics day. Methanol used, 3 plants, A. P. S. at least caused 25–29 mm maximum size zone inhibition on bacterial lawns. Minimum inhibitory concentration (MIC) minimum bactericidal (MBC) values methanol recorded. The extract had 0.29 mg/ml lowest MIC value 0.67 mg/ml MBC value, against signifying effectivity; but, it highest 3.41 mg/ml. 4.27 mg/ml other including E. . Qualitative phytochemical analysis done these information leading phytochemicals presented retrieved PubChem database. Thus, three effective-most controlling MDR-UTI vitro which can be promoted complementary medicine.