Lincosamide resistance is less frequent in Denmark in Staphylococcus pseudintermedius from first-time canine superficial pyoderma compared with skin isolates from clinical samples with unknown clinical background.

摘要: BACKGROUND Antimicrobial resistance may be overestimated in bacterial isolates from clinical samples because veterinarians often submit cases of treatment failure or recurrent cases, which are more frequently associated with resistant strains. HYPOTHESIS/OBJECTIVES To assess to what extent the prevalence antimicrobial Staphylococcus pseudintermedius isolated first-time superficial pyoderma differs canine skin unknown background. ANIMALS Two study groups were enrolled Denmark between March 2012 and October 2013: 57 dogs no prior (Group A); 289 different for specimens submitted culture during (Group B). METHODS One S. pseudintermedius isolate each dog was confirmed by MALDI-TOF mass spectrometry tested susceptibility broth microdilution. Resistance levels two compared Fisher's exact test. RESULTS Clindamycin less frequent Group A (14%) than Group B (27%) (P = 0.02). Similar trends observed amoxicillin-clavulanic acid (1.8 versus 4.8%), chloramphenicol (8.8 14.5%), enrofloxacin 3.5%), oxacillin 4.8%) trimethoprim/sulfamethoxazole (3.5 5.9%). Oxacillin significantly six seven non-β-lactams. CONCLUSIONS AND CLINICAL IMPORTANCE The lincosamide is markedly influenced patients' history. limit selection multidrug-resistant bacteria, lincosamides appropriate empirical choices even though not infrequent. Culture testing are, however, recommended all patients.