Endocrinological and pathological effects of anabolic-androgenic steroid in male rats.

摘要: Many athletes use drugs, especially anabolic androgenic steroids (AAS), but there are few reports on the endocrinological and pathological changes in AAS abusers. In this study we reported results of examinations rats administered also physical changes. We separated 37 male Wistar (7 weeks old) into 3 groups: Group A was medicated with nandrolone decanoate, metenolone acetate, dromostanolone; B decanoate saline; C given only saline. They were subcutaneous injections medications or control vehicle once a week for 6 weeks. Medications stopped 4 weeks, then resumed another After that, sacrificed. Serum testosterone level significantly higher than that C. dihydrotestosterone both Groups estradiol-17β levels evaluation, heart, testis, adrenal gland severely damaged. These findings indicate is high degree risk related to AAS.