作者: Andrea Ferreira Haddad , Eduardo Costa , Pedro Pimenta de Mello Spineti , Armando Leão Ferreira Neto , André Filipe Marcondes Vieira
DOI: 10.1016/J.BJID.2021.101549
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摘要: Abstract Objectives To assess the efficacy of hydroxychloroquine in combination with azithromycin terms clinical and biochemical outcomes adult patients COVID-19 hospitalized for acute respiratory distress syndrome (ARDS), to describe occurrence adverse events. Method Retrospective comparative study, based a quaternary private hospital Rio de Janeiro, Brazil, involving 193 mild moderate related ARSD, analyzing treatment on outcomes. Results The active group comprised 101 (52.3%) using associated control 92 (47.7%) who did not take these medications. Median age was 59 (47–70) 65 (47−77) (p 0.05). No difference mortality, duration non-invasive oxygen use or hospitalization seen between groups. therapeutic regimen well tolerated, only eight (7.9%) presenting gastrointestinal symptoms withdrawn due QTc prolongation. Conclusions Patients treated combined had similar This considered ineffective ARDS few non-severe