The burden of chronic kidney disease in renal transplant recipients.

作者: Vanji Karthikeyan , Jolanta Karpinski , Rama C. Nair , Greg Knoll

DOI: 10.1046/J.1600-6143.2003.00315.X

关键词:

摘要: The National Kidney Foundation has developed guidelines for the diagnosis and classification of chronic kidney disease (CKD) but it is not known whether these are applicable to renal transplant recipients. This study determined prevalence CKD according stages defined in guidelines, complications related was stage 459 present 412 patients (90%) 60% were Stage 3 with a glomerular filtration rate (GFR) between 30 59 mL/min/1.73 m2. anemia increased from 0% 1 33% 5 (p < 0.001). Hypertension 86% 100% = 0.02). number anti-hypertensives per patient 0.7 2.3 1.1 2.7 We conclude that highly prevalent by may help clinicians identify at risk target appropriate therapy improve outcomes.

参考文章(33)
D. Reaich, T. H. J. Goodship, S. M. Channon, K. A. Graham, S. Downie, Correction of acidosis in hemodialysis decreases whole-body protein degradation. Journal of The American Society of Nephrology. ,vol. 8, pp. 632- 637 ,(1997) , 10.1681/ASN.V84632
Philip F. Halloran, Call for revolution: a new approach to describing allograft deterioration. American Journal of Transplantation. ,vol. 2, pp. 195- 200 ,(2002) , 10.1034/J.1600-6143.2002.20301.X
John S. Gill, Rekha Abichandani, Samina Khan, Annamaria T. Kausz, Brian J.G. Pereira, Opportunities to improve the care of patients with kidney transplant failure. Kidney International. ,vol. 61, pp. 2193- 2200 ,(2002) , 10.1046/J.1523-1755.2002.00373.X
Yadong Cui, Roger S Blumenthal, Jodi A Flaws, Maura K Whiteman, Patricia Langenberg, Paul S Bachorik, Trudy L Bush, None, Non-high-density lipoprotein cholesterol level as a predictor of cardiovascular disease mortality. JAMA Internal Medicine. ,vol. 161, pp. 1413- 1419 ,(2001) , 10.1001/ARCHINTE.161.11.1413
Donald E. Hricik, Anemia after kidney transplantation--is the incidence increasing? American Journal of Transplantation. ,vol. 3, pp. 771- 772 ,(2003) , 10.1034/J.1600-6143.2003.00174.X
Joel D Kopple, Tom Greene, W Cameroon Chumlea, Donna Hollinger, Bradley J Maroni, Donna Merrill, Laura K Scherch, Gerald Schulman, Shin-Ru Wang, Gail S Zimmer, Modification of Diet in Renal Disease Study Group, Relationship between nutritional status and the glomerular filtration rate: Results from the MDRD Study Kidney International. ,vol. 57, pp. 1688- 1703 ,(2000) , 10.1046/J.1523-1755.2000.00014.X
Josef Coresh, G. Laura Wei, Geraldine McQuillan, Fredrick L Brancati, Andrew S. Levey, Camille Jones, Michael J. Klag, Prevalence of High Blood Pressure and Elevated Serum Creatinine Level in the United States Archives of Internal Medicine. ,vol. 161, pp. 1207- 1216 ,(2001) , 10.1001/ARCHINTE.161.9.1207
Gerald J. Beck, Richard L. Berg, Cecil H. Coggins, Jennifer J. Gassman, Lawrence G. Hunsicker, Mark D. Schluchter, George W. Williams, The modification of diet in renal disease study group Controlled Clinical Trials. ,vol. 12, pp. 566- 586 ,(1991) , 10.1016/0197-2456(91)90069-X
Gunter Wolf, Sheldon Chen, Dong Cheol Han, Fuad N. Ziyadeh, Leptin and renal disease American Journal of Kidney Diseases. ,vol. 39, pp. 1- 11 ,(2002) , 10.1053/AJKD.2002.29865
AS Levey, JA Beto, BE Coronado, G Eknoyan, RN Foley, BL Kasiske, MJ Klag, LU Mailloux, CL Manske, KB Meyer, PS Parfrey, MA Pfeffer, NK Wenger, PW Wilson, JT Wright, Controlling the epidemic of cardiovascular disease in chronic renal disease: What do we know? What do we need to learn? Where do we go from here? National Kidney Foundation Task Force on Cardiovascular Disease American Journal of Kidney Diseases. ,vol. 32, pp. 853- 906 ,(1998) , 10.1016/S0272-6386(98)70145-3