Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases.
作者： Ali Roohbakhsh , Hamideh Parhiz , Fatemeh Soltani , Ramin Rezaee , Mehrdad Iranshahi
DOI: 10.1016/J.LFS.2014.12.030
关键词:
摘要: … It is well known that apoptosis is involved in the pathology of … administered Hsd (1, 3, or 10 mg/kg) or aspirin (50 mg/kg) on … , a number of targets including NF-κB, TNF-α, IL-1β, IL-6, Nrf2…
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researchgate.net 参考文章(89)
Aditi Aggarwal, Vaibhav Gaur, Anil Kumar, Possible nitric oxide mechanism in the protective effect of hesperidin against ischemic reperfusion cerebral injury in rats. Indian Journal of Experimental Biology. ,vol. 49, pp. 609- 618 ,(2011)
A Rossitto, S Kirjavainen, A M Forestieri, E M Galati, M T Monforte, A Trovato, Biological effects of hesperidin, a Citrus flavonoid. (Note III): antihypertensive and diuretic activity in rat. Farmaco. ,vol. 51, pp. 219- 221 ,(1996)
Jayasudha Elavarasan, Prema Velusamy, Thellamudhu Ganesan, Suresh Krishna Ramakrishnan, Devaraja Rajasekaran, Kalaiselvi Periandavan, Hesperidin-mediated expression of Nrf2 and upregulation of antioxidant status in senescent rat heart Journal of Pharmacy and Pharmacology. ,vol. 64, pp. 1472- 1482 ,(2012) , 10.1111/J.2042-7158.2012.01512.X
Miyako Ikemura, Yasuto Sasaki, John C. Giddings, Junichiro Yamamoto, Preventive effects of hesperidin, glucosyl hesperidin and naringin on hypertension and cerebral thrombosis in stroke-prone spontaneously hypertensive rats Phytotherapy Research. ,vol. 26, pp. 1272- 1277 ,(2012) , 10.1002/PTR.3724
Johanna M Geleijnse, Lenore J Launer, Deirdre AM van der Kuip, Albert Hofman, Jacqueline CM Witteman, Inverse association of tea and flavonoid intakes with incident myocardial infarction: the Rotterdam Study The American Journal of Clinical Nutrition. ,vol. 75, pp. 880- 886 ,(2002) , 10.1093/AJCN/75.5.880
A. Garg, S. Garg, L. J. D. Zaneveld, A. K. Singla, Chemistry and pharmacology of the citrus bioflavonoid hesperidin Phytotherapy Research. ,vol. 15, pp. 655- 669 ,(2001) , 10.1002/PTR.1074
Masaki YAMAMOTO, Hiroko JOKURA, Atsushi SUZUKI, Tadashi HASE, Akira SHIMOTOYODOME, Effects of Continuous Ingestion of Hesperidin and Glucosyl Hesperidin on Vascular Gene Expression in Spontaneously Hypertensive Rats Journal of Nutritional Science and Vitaminology. ,vol. 59, pp. 470- 473 ,(2013) , 10.3177/JNSV.59.470
Selvaraj Aranganathan, Jayabal Panneer Selvam, Namasivayam Nalini, Hesperetin exerts dose dependent chemopreventive effect against 1,2-dimethyl hydrazine induced rat colon carcinogenesis Investigational New Drugs. ,vol. 27, pp. 203- 213 ,(2009) , 10.1007/S10637-008-9158-8
Muzheng Yang, Takuji Tanaka, Yoshinobu Hirose, Takashi Deguchi, Hideki Mori, Yukimichi Kawada, Chemopreventive effects of diosmin and hesperidin on N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine‐induced urinary‐bladder carcinogenesis in male ICR mice International Journal of Cancer. ,vol. 73, pp. 719- 724 ,(1997) , 10.1002/(SICI)1097-0215(19971127)73:5<719::AID-IJC18>3.0.CO;2-0
Takuji Tanaka, Takahiro Tanaka, Mayu Tanaka, Toshiya Kuno, Cancer Chemoprevention by Citrus Pulp and Juices Containing High Amounts of β-Cryptoxanthin and Hesperidin BioMed Research International. ,vol. 2012, pp. 516981- 516981 ,(2012) , 10.1155/2012/516981