Comparing participants and nonparticipants recruited for an effectiveness study of nicotine replacement therapy.

摘要: Background: Interventions for smoking cessation have been typically evaluated on reactively recruited samples in clinical trials (efficacy trials). However, to an impact rates a general population, the intervention should also be with proactively representative (effectiveness trials).Purpose: The characteristics of participants and two groups nonparticipants population-based nicotine replacement therapy study were compared.Methods: All members large New England Veterans’ Administration Medical Center contacted, interviews completed 3,239 identified smokers (at least 10 cigarettes per day). At end interview, all offered participation multiple study. Of interviewed smokers, 2,915 verbally agreed participate (90%). those who gave initial verbal consent, 2,054 returned written informed consent form became (70%).Results: (full group) differed significantly from both nonparticipant groups—that is, but declined by active refusal (survey only passively refused failing return (verbal group). Participants more likely married, younger, female; live others; previously used or considered using therapy. survey group was precontemplation stage (54%), whereas contemplation (46%) preparation (35%). intermediate other stage-of-change characteristics.Conclusions: An important finding that it is possible recruit proportion sample are differ significant ways either actively decline participation.