Microsatellite analysis and susceptibility to FCZ of Candida glabrata invasive isolates in Sfax Hospital, Tunisia.
作者： S. Abbes , H. Sellami , A. Sellami , F. Makni , N. Mahfoudh
DOI: 10.3109/13693786.2010.493561
关键词:
摘要: We have noted that, during the last few years, there has been a redistribution of most common Candida species with an increase in non-C. albicans species, particularly glabrata. In many countries, high frequency glabrata shows highest resistance rates. The main objective this investigation was to analyze genotypic variability invasive C. isolates recovered over period six years and assess their vitro susceptibility fluconazole determine possible existence relationships between genotype susceptibility. collected 50 (21.4%) from January 2001 December 2007. profiles as determined by E-test method showed that 8.3% were resistant fluconazole. typing three microsatellite markers RPM2, MTI ERG3 demonstrated 12 multilocus genotypes distributed irregularly predominance G1 (38%). A cluster (G9) found among collec...
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