Evaluating pulsatile ocular blood flow analysis in normal and treated glaucomatous eyes

作者: Ali Aydin , Gadi Wollstein , Lori Lyn Price , Joel S. Schuman

DOI: 10.1016/S0002-9394(03)00237-X

关键词:

摘要: Abstract Purpose : To evaluate pulsatile ocular blood flow (POBF) analysis in normal subjects and glaucoma patients by comparison of POBF measurements with functional (as determined visual field [VF]) structural optical coherence tomography [OCT]) measures. Design Prospective, cross-sectional study. Methods Forty-one eyes 24 consecutive 20 10 healthy were studied; was performed on all at the same visit as VF testing OCT retinal nerve fiber layer (NFL) thickness measurement. The mean results glaucomatous compared for each method. Correlation between obtained modality discriminating power using receiver operator characteristic curves tested. Results (standard deviation [SD]) group 1,010.4 (292.8) μl/min 989.3 (305.5) ( P = .90). Significant differences groups found pattern standard .02, .004, respectively) NFL .003). area under higher indexes than parameters distinguishing eyes. Conclusions wide range values low limits clinical use device patients.

参考文章(47)
Yit C. Yang, Mark F. G. Hulbert, Mark Batterbury, Louis G. Clearkin, Pulsatile ocular blood flow measurements in healthy eyes: reproducibility and reference values. Journal of Glaucoma. ,vol. 6, pp. 175- 179 ,(1997) , 10.1097/00061198-199706000-00007
Andrew Morgan, Sarah Hosking, Ocular blood flow tonometer reproducibility: the effect of operator experience and mode of application Ophthalmic and Physiological Optics. ,vol. 21, pp. 401- 406 ,(2001) , 10.1046/J.1475-1313.2001.00598.X
D R Trew, S E Smith, Postural studies in pulsatile ocular blood flow: I. Ocular hypertension and normotension. British Journal of Ophthalmology. ,vol. 75, pp. 66- 70 ,(1991) , 10.1136/BJO.75.2.66
K Bailey Freund, Lawrence A Yannuzzi, John A Sorenson, None, Age-related Macular Degeneration and Choroidal Neovascularization American Journal of Ophthalmology. ,vol. 115, pp. 786- 791 ,(1993) , 10.1016/S0002-9394(14)73649-9
David R. Trew, C. Bruce James, Simon H. L. Thomas, Richard Sutton, Stephen E. Smith, Factors influencing the ocular pulse--the heart rate. Graefes Archive for Clinical and Experimental Ophthalmology. ,vol. 229, pp. 553- 556 ,(1991) , 10.1007/BF00203321
Michael Quigley, A New Pressure Attenuation Index to Evaluate Retinal Circulation Archives of Ophthalmology. ,vol. 117, pp. 84- 89 ,(1999) , 10.1001/ARCHOPHT.117.1.84
MARCELO T. NICOLELA, PETER HNIK, STEPHEN M. DRANCE, Scanning Laser Doppler Flowmeter Study of Retinal and Optic Disk Blood Flow in Glaucomatous Patients American Journal of Ophthalmology. ,vol. 122, pp. 775- 783 ,(1996) , 10.1016/S0002-9394(14)70373-3
A. Harris, G.L. Spaeth, R.C. Sergott, L.J. Katz, Louis B. Cantor, B.J. Martin, Retrobulbar arterial hemodynamic effects of betaxolol and timolol in normal-tension glaucoma. American Journal of Ophthalmology. ,vol. 120, pp. 168- 175 ,(1995) , 10.1016/S0002-9394(14)72604-2