Relations between upper abdominal symptoms and gastric distension abnormalities in dysmotility like functional dyspepsia and after vagotomy.

摘要: Postprandial bloating and fullness are commonly found both in dysmotility like functional dyspepsia, after vagotomy but the relation between gastric accommodation symptom production has not been investigated. Intragastric pressure levels symptoms developed during controlled distension of fundus were recorded nine patients with seven truncal vagotomy, 11 healthy volunteers. The procedure was repeated ingestion a liquid nutrient meal (250 ml; 250 kcal). Gastric tone, expressed as average value over period lower controls (median: 11.3 mm Hg) than either dyspeptic 16.48 or postvagotomy 19.12 (p < 0.05). Meal reduced tone controls, no significant change occurred dyspepsia patients. Volumes at which discomfort elicited by fasting 210 ml) 180 volunteers 660 Discomfort thresholds unaffected ingestion. These results suggest that disturbance relaxation may be related to development while similarities impaired due an underlying vagal defect.