Potential of PVA-doped bacterial nano-cellulose tubular composites for artificial blood vessels
作者： Jingyu Tang , Luhan Bao , Xue Li , Lin Chen , Feng F. Hong
DOI: 10.1039/C5TB01144B
关键词:
摘要: Bacterial nano-cellulose (BNC) hydrogel has been suggested as a promising biomaterial for artificial blood vessels. However, some properties of BNC do not achieve all the requirements native vessel – compliance, instance. In order to improve tubes, poly(vinyl alcohol) (PVA) was introduced in tubes make composites. Two types pristine with different inner structures were produced two bioreactors. A PVA tube and PVA–BNC tubular composites made comparison by using thermally-induced phase separation method. The morphology, water permeability, cytotoxicity, mechanical properties, including axial stretch strength, suture retention, burst pressure, compliance evaluated compared. results indicated that impregnated into then significantly improved BNC, especially permeability. itself played great role performances skeleton base material. composite could constitute new candidates vascular grafts.
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