Mechanical properties of biodegradable small-diameter chitosan artificial vascular prosthesis.

作者: Xiaoying Kong , Baoqin Han , Haixia Wang , Hui Li , Wenhua Xu

DOI: 10.1002/JBM.A.34136

关键词:

摘要: Initial clinical feasibility with the small-diameter chitosan artificial vascular prosthesis has been reported previously. Here, we present results of mechanical properties 2, 3, and 4 mm inner diameter (ID) compare some native blood vessel dog femoral artery. Thickness wall measurement demonstrated average thickness ID artery 3 were 0.54 ± 0.022 mm, 0.71 0.032 0.79 0.026 0.67 0.22 (n = 20). Water absorption rate 226.02% 8.17%, 216.13% 4.86%, 205.69% 4.34% obtained from 2-, 3-, 4-mm-diameter 12), respectively. osmotic pressure was 39.25 3.35 mmHg, 34.2 4.54 28.00 2.72 mmHg 20), amount 4-cm-diameter 20) 4.90 0.47 mL/(min cm(2) ), 5.51 0.21 6.24 The ruptured stretching 1.59% 0.14%, 1.99% 0.24%, 2.52% 0.21%, 32.16% 2.15%, longitudinal tensile strength 8.58 1.98 N, 19.75 4.07 22.92 3.85 18.76 2.05 suture retention in dry condition is 5.80 0.51 7.01 0.32 8.49 0.56 7.92 0.39 wet 3.87 0.43 4.73 0.37 5.63 0.36 compliance 6.5% 2.6%/100 5.2% 1.5%/100 4.7% 1.3%/100 10.3% 2.3%/100 data here fulfill quality requirement use this kind biodegradable small prosthesis.

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