Do Alpha-Blockers Prevent the Occurrence of Acute Urinary Retention?

摘要: Acute urinary retention (AUR) is a common complication of benign prostatic hyperplasia (BPH) and the incidence varies widely from 0.4 to 25% per year in men seen urology practices. It has been estimated that AUR indication for surgery around 25–30% patients undergoing transurethral resection prostate (TURP) emergency TURP associated with greater morbidity than elective TURP. Risk factors include lower tract symptoms (LUTS), depressed peak flow rate, enlarged prostate, high postvoid residual (PVR) urine old age. Alfuzosin shown significantly increase maximum rate relieve bladder outlet obstruction, resulting reduction PVR urine. A pooled analysis 11 placebo-controlled studies involving 1,470 LUTS suggestive BPH indicates improvements were observed treated alfuzosin placebo. 6-month placebo controlled study 518 reported 0.4% group compared 2.4% (p = 0.04). These positive effects on could be related alfuzosin-treated patients.