Mitomycin C application in resistant caustic esophageal stricture

摘要: Background/purpose Caustic esophageal strictures still represent a catastrophic problem in children of our country. Management protocol is usually started by regular dilatation which multiple sessions may be needed until the resolution dysphagia; however, many cases endoscopic fails and therefore replacement eventually required. Our aim to assess role mitomycin C application management caustic stricture refractory dilatation. Patients methods with resistant were subjected topical on site after followed up clinically using validated dysphagia score improvement dysphagia, radiologically contrast esophagogram endoscopically confirm stricture. Results analyzed compared results control group managed at institution protocol. During period January 2008 June 2010, 12 patients unit whom six had short ( 3 cm). Topical resulted clinical radiological 83% 66% respectively, 44 (eight out 18 stricture) 25% (two eight long group. Conclusion Mitomycin can markedly improve outcome stricture, reducing number required for However, double-blinded randomized controlled trial prove its effectiveness. Keywords : dilatation,