Visual adaptation and novelty responses in the superior colliculus

摘要: The brain’s ability to ignore repeating, often redundant, information while enhancing novel processing is paramount survival. When stimuli are repeatedly presented, the response of visually sensitive neurons decreases in magnitude, that is, adapt or habituate, although mechanism not yet known. We monitored activity visual superior colliculus (SC) rhesus monkeys who actively fixated repeated events were presented. dissociated adaptation from habituation as mechanisms decrement by using a Bayesian model adaptation, and employing paradigm including rare trials included an oddball stimulus was either brighter dimmer. If recovery should be seen only for stimulus; if habituation, (‘dishabituation’) both dimmer stimuli. observed reduction magnitude initial transient increase onset latency with repetition all responsive SC. Response successfully captured model, which also predicted effects presentation rate luminance changes. However, subset sustained stimuli, novelty signal akin dishabituation late profile model. This suggests SC integrate rapidly discounted about repeating events, support efficient selection cluttered dynamic world.